Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21510835 | 1.00 | CA2 (0.55) | CA2TSHRHSD17B10LMNACA1 | |
| SCHEMBL5002569 | 0.90 | MAPT (0.57) | CA2TSHRHSD17B10LMNAENPP2 | |
| SCHEMBL28887988 | 0.90 | MAPT (0.57) | CA2TSHRHSD17B10LMNAENPP2 | |
| SCHEMBL2922447 | 0.90 | POLB (0.49) | CA2TSHRHSD17B10LMNACA1 | |
| SCHEMBL11114440 | 0.90 | MAPT (0.61) | CA2TSHRHSD17B10LMNAMAPT | |
| SCHEMBL2921402 | 0.90 | TSHR (0.68) | CA2TSHRHSD17B10LMNACA1 | |
| SCHEMBL5010591 | 0.86 | KIF11 (0.50) | CA2TSHRHSD17B10KMT2A | |
| SCHEMBL9115481 | 0.84 | TSHR (0.51) | CA2TSHRHSD17B10LMNACA1 | |
| SCHEMBL8355889 | 0.78 | CA2 (0.75) | CA2HSD17B10LMNACA1CA12 | |
| SCHEMBL2717291 | 0.78 | ESR1 (0.50) | CA2HSD17B10LMNACA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143407-A2 | Process for preparing aromatic polyethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-05 | — | — | EP | disclosed |