Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29014812 | 0.84 | NOTUM (0.40) | MAPTNOTUM | |
| SCHEMBL28998849 | 0.78 | MAPT (0.39) | MAPTCYP2C19POLBNOTUMGABRP | |
| SCHEMBL10021552 | 0.71 | MAPT (0.50) | MAPTCYP2C19POLBNOTUMAPLNR | |
| SCHEMBL29173291 | 0.69 | PDK2 (0.33) | — | |
| SCHEMBL29226681 | 0.68 | S1PR5 (0.38) | MAPTPOLBS1PR1S1PR5 | |
| SCHEMBL2222066 | 0.68 | MAPT (0.39) | MAPTPOLBNOTUMAPLNRS1PR1 | |
| SCHEMBL22978696 | 0.67 | ALDH1A1 (0.45) | MAPTNOTUMTSHR | |
| SCHEMBL29005251 | 0.67 | MAPT (0.31) | MAPTAPLNR | |
| SCHEMBL13101700 | 0.67 | APLNR (0.38) | MAPTPOLBAPLNRS1PR1S1PR5 | |
| SCHEMBL13905844 | 0.65 | CHRM1 (0.38) | MAPTPOLBS1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993850-B | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2024-03-29 | — | — | CN | disclosed |