SCHEMBL29005251

SCHEMBL29005251

CC1CC(C(=O)O)CC(C)N1C(F)C(F)F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29005186 0.80 CHRNB2 (0.41)
SCHEMBL26488863 0.78 MAPT (0.41) MAPTAPLNR
SCHEMBL24423041 0.74 APLNR (0.37) MAPTAPLNR
SCHEMBL29214260 0.67 MAPT (0.34) MAPTAPLNR
SCHEMBL27678062 0.65 GABRR1 (0.36) MAPTAPLNR
SCHEMBL11388564 0.64 LMNA (0.52)
SCHEMBL8947045 0.64 LMNA (0.52)
SCHEMBL29224380 0.64 CYP2C19 (0.33) APLNR
SCHEMBL28998849 0.64 MAPT (0.39) MAPT
SCHEMBL850636 0.64 APLNR (0.43) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116134018-A 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor 默沙东有限责任公司 2023-05-16 CN disclosed