Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.52 |
| ▸ | BAG3 | O95817 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29214934 | 1.00 | PPARG (0.58) | PPARGALDH1A1SMN1; SMN2MITFRAB9A | |
| SCHEMBL29214808 | 0.86 | MMP1 (0.67) | ALDH1A1SMN1; SMN2MITFRAB9APOLB | |
| SCHEMBL29214806 | 0.86 | MMP1 (0.67) | ALDH1A1SMN1; SMN2MITFRAB9APOLB | |
| SCHEMBL28374629 | 0.83 | PPARG (0.81) | PPARGALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL21783127 | 0.83 | PPARG (0.81) | PPARGALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL21783159 | 0.83 | PPARG (0.76) | PPARGALDH1A1SMN1; SMN2MITFRAB9A | |
| SCHEMBL29214736 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MITFRAB9APOLB | |
| SCHEMBL29214732 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MITFRAB9APOLB | |
| SCHEMBL14900942 | 0.81 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2MITFRAB9APOLB | |
| SCHEMBL13446896 | 0.81 | MMP1 (0.73) | ALDH1A1SMN1; SMN2MITFRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777049-B | Thiazolidinedione HDAC inhibitor, preparation method and application | 南京市鸿舜医药科技有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117777049-A | Thiazolidinedione HDAC inhibitor, preparation method and application | 南京市鸿舜医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |