Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357664 | 0.84 | HRH3 (0.47) | HRH3LMNAGLAHSD17B10CYP2A13 | |
| SCHEMBL13537253 | 0.79 | HRH3 (0.48) | HRH3LMNAGLAHTR6HSD17B10 | |
| SCHEMBL3358883 | 0.79 | CTSB (0.59) | HRH3LMNAHTR6CNR2 | |
| SCHEMBL29215998 | 0.76 | CYP2A13 (0.40) | HRH3HSD17B10CYP2A13ALOX15MAPK1 | |
| SCHEMBL28566679 | 0.76 | ADRB2 (0.41) | LMNAHTR6 | |
| SCHEMBL3358110 | 0.76 | HRH3 (0.55) | HRH3LMNAGLAHSD17B10CYP2A13 | |
| SCHEMBL5254444 | 0.75 | CYP2C9 (0.58) | HRH3HSD17B10CYP2A13ALOX15CCR5 | |
| SCHEMBL2802106 | 0.74 | CYP2A13 (0.61) | LMNAHSD17B10CYP2A13ALOX15MAPK1 | |
| SCHEMBL13537351 | 0.73 | HRH3 (0.55) | HRH3LMNAGLAHSD17B10CYP2A13 | |
| SCHEMBL4468135 | 0.73 | HSD17B10 (0.51) | HSD17B10CYP2A13ALOX15CCR5CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444523-A | Compounds as SMARCA2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-07-18 | — | — | CN | disclosed |