Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358110 | 0.89 | HRH3 (0.55) | HRH3LMNAGLAICMTCYP2A13 | |
| SCHEMBL3354205 | 0.88 | LMNA (0.46) | HRH3LMNAMAPTALDH1A1ADRB2 | |
| SCHEMBL3353571 | 0.87 | ACHE (0.51) | LMNAGLAICMTALDH1A1TSHR | |
| SCHEMBL3352639 | 0.86 | NR1H2 (0.53) | LMNAGLAICMTALDH1A1TSHR | |
| SCHEMBL3350921 | 0.86 | ACHE (0.50) | LMNAGLAICMTALDH1A1TSHR | |
| SCHEMBL3351981 | 0.86 | ICMT (0.55) | HRH3ICMTCYP2A13CYP2C9ALOX15 | |
| SCHEMBL29215987 | 0.84 | HRH3 (0.47) | HRH3LMNAGLAICMTCYP2A13 | |
| SCHEMBL3358883 | 0.79 | CTSB (0.59) | HRH3LMNAMAPTALDH1A1 | |
| SCHEMBL13537253 | 0.79 | HRH3 (0.48) | HRH3LMNAGLAICMTCYP2A13 | |
| SCHEMBL3353615 | 0.75 | HRH3 (0.41) | HRH3ICMTCYP2A13CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |