Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701796 | 0.78 | KMT2A (0.59) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL2615559 | 0.74 | G6PC1 (0.57) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL7373897 | 0.74 | G6PC1 (0.57) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL14667522 | 0.74 | G6PC1 (0.57) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL11231257 | 0.68 | KMT2A (0.49) | KMT2AMEN1G6PC1LMNAL3MBTL1 | |
| SCHEMBL4379211 | 0.68 | G6PC1 (0.50) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL4279968 | 0.68 | FURIN (0.56) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL7968589 | 0.68 | FURIN (0.56) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL4037961 | 0.68 | FURIN (0.56) | KMT2AMEN1G6PC1LMNAMAPK1 | |
| SCHEMBL14399920 | 0.67 | KMT2A (0.56) | KMT2AMEN1G6PC1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453760-B | APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2024-05-24 | — | — | CN | disclosed |