Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373897 | 0.79 | G6PC1 (0.57) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL14667522 | 0.79 | G6PC1 (0.57) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2615559 | 0.79 | G6PC1 (0.57) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL10498731 | 0.76 | ALDH1A1 (0.50) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11701796 | 0.73 | KMT2A (0.59) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11699938 | 0.71 | ALDH1A1 (0.50) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL21401699 | 0.68 | G6PC1 (0.46) | G6PC1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15549217 | 0.68 | ALDH1A1 (0.47) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL29217306 | 0.68 | KMT2A (0.53) | G6PC1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4037961 | 0.68 | FURIN (0.56) | G6PC1KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133341-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | disclosed |