Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30884124 | 0.79 | ALOX5 (0.46) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL27443616 | 0.75 | ALOX5 (0.53) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL30416339 | 0.75 | ALOX5 (0.52) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL23833005 | 0.75 | ALOX5 (0.52) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL5320260 | 0.73 | ALOX5 (0.48) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL28967230 | 0.73 | ALOX5 (0.44) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL27718331 | 0.71 | HPGD (0.52) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL27739386 | 0.70 | SMN1; SMN2 (0.53) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL23833148 | 0.70 | ALOX5 (0.47) | ALOX5LOXL2PKMRAB9AALDH1A1 | |
| SCHEMBL23832970 | 0.70 | HDAC3 (0.48) | ALOX5LOXL2PKMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756742-A | Benzothiazole compound or salt thereof, preparation method and application thereof | 徐州医科大学 | 2024-03-26 | — | — | CN | disclosed |