Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323342 | 0.91 | HDAC1 (0.51) | ALOX5HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL30416339 | 0.79 | ALOX5 (0.52) | ALOX5HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL23833005 | 0.79 | ALOX5 (0.52) | ALOX5HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL7596070 | 0.75 | SMN1; SMN2 (0.58) | ALOX5HPGDALDH1A1KMT2APKM | |
| SCHEMBL2782358 | 0.74 | MGLL (0.46) | ALOX5HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL23833148 | 0.73 | ALOX5 (0.47) | ALOX5HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL29217750 | 0.73 | ALOX5 (0.47) | ALOX5HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9316764 | 0.73 | PKM (0.61) | ALOX5HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL4703104 | 0.72 | HTT (0.71) | HPGDALDH1A1MEN1KMT2APKM | |
| SCHEMBL28712690 | 0.72 | SMN1; SMN2 (0.54) | ALOX5HPGDALDH1A1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113644-A2 | NEW HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-10-11 | — | — | WO | disclosed |