Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415482 | 0.77 | RAB9A (0.64) | RAB9ASMN1; SMN2ALDH1A1NPC1HSD11B1 | |
| SCHEMBL10061706 | 0.76 | RAB9A (0.62) | RAB9ASMN1; SMN2ALDH1A1NPC1HSD11B1 | |
| SCHEMBL2755870 | 0.76 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2ALDH1A1NPC1HSD11B1 | |
| SCHEMBL18415494 | 0.72 | RAB9A (0.54) | RAB9ASMN1; SMN2ALDH1A1NPC1HSD11B1 | |
| SCHEMBL17789281 | 0.70 | KMT2A (0.47) | RAB9ASMN1; SMN2ALDH1A1NPC1HSD11B1 | |
| SCHEMBL14454192 | 0.69 | MEN1 (0.65) | RAB9ASMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL14350120 | 0.69 | MEN1 (0.47) | RAB9ASMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL16388796 | 0.67 | KMT2A (0.50) | RAB9ASMN1; SMN2ALDH1A1NPC1HSD11B1 | |
| SCHEMBL25587466 | 0.67 | MAPT (0.42) | RAB9ASMN1; SMN2ALDH1A1NPC1HSD11B1 | |
| SCHEMBL14664143 | 0.66 | MAPT (0.50) | RAB9ASMN1; SMN2ALDH1A1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | GIVAUDAN SA (CH) | 2012-04-19 | — | — | US | claimed |
| EP-2427170-A2 | ORGANIC COMPOUNDS HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128026-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | WO | claimed |
| US-8664261-B2 | Organic compounds having cooling properties | GIVAUDAN S.A. (CH) | 2014-03-04 | — | — | US | disclosed |
| US-8664261-B2 | Organic compounds having cooling properties | GIVAUDAN S.A. (CH) | 2014-03-04 | — | — | US | disclosed |
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | GIVAUDAN SA (CH) | 2012-04-19 | — | — | US | disclosed |
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | GIVAUDAN SA (CH) | 2012-04-19 | — | — | US | disclosed |
| EP-2427170-A2 | ORGANIC COMPOUNDS HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128026-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128026-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095042-A1 | Organic Compounds Having Cooling Properties | ME3, ME2, MSMO1 | RAB9A 3627/4885SMN1; SMN2 3743/4885ALDH1A1 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.