Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218520 | 0.93 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL29218762 | 0.82 | EPHX1 (0.41) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL25041452 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL29218910 | 0.81 | MAPT (0.43) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL25041545 | 0.79 | KDM4E (0.43) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL25039430 | 0.79 | MEN1 (0.43) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL29218717 | 0.78 | EPHX1 (0.44) | KMT2AMEN1ALDH1A1EPHX1EPHX2 | |
| SCHEMBL25039262 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL25039630 | 0.77 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1KDM4EEPHX1 | |
| SCHEMBL28803334 | 0.77 | L3MBTL1 (0.42) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |