Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218696 | 0.87 | MGLL (0.44) | EPHX2KIF11GAACNR2 | |
| SCHEMBL29218640 | 0.82 | KMT2A (0.47) | EPHX1EPHX2KIF11GAACNR2 | |
| SCHEMBL29218799 | 0.82 | PTGIR (0.49) | EPHX2RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29218556 | 0.82 | L3MBTL1 (0.49) | EPHX1EPHX2KIF11GAARAB9A | |
| SCHEMBL29218546 | 0.81 | PRSS1 (0.39) | EPHX1EPHX2KMT2AMEN1MAPT | |
| SCHEMBL29218520 | 0.81 | ALDH1A1 (0.54) | EPHX1EPHX2KIF11GAARAB9A | |
| SCHEMBL25039677 | 0.81 | CNR2 (0.44) | EPHX1EPHX2KIF11GAACNR2 | |
| SCHEMBL29218717 | 0.80 | EPHX1 (0.44) | EPHX1EPHX2KIF11GAACNR2 | |
| SCHEMBL29218805 | 0.80 | MAPT (0.37) | CNR2CNR1RAB9AALDH1A1KMT2A | |
| SCHEMBL25042225 | 0.80 | CNR2 (0.43) | EPHX1EPHX2KIF11GAACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |