Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218677 | 0.94 | HDAC3 (0.39) | HDAC8HDAC6HDAC3HDAC11DEGS1 | |
| SCHEMBL29218827 | 0.88 | SYK (0.39) | ALDH1A1HPGDSYKMAPTLMNA | |
| SCHEMBL29218572 | 0.86 | EML4 (0.36) | HDAC8HDAC6HDAC3HDAC11SYK | |
| SCHEMBL29218654 | 0.85 | EPHX2 (0.33) | HDAC8HDAC6HDAC3HDAC11SYK | |
| SCHEMBL29218716 | 0.82 | ALDH1A1 (0.43) | HDAC8HDAC6ALDH1A1GAAMAPT | |
| SCHEMBL29218783 | 0.82 | MAPT (0.34) | ALDH1A1SYKMAPTNPC1FFAR4 | |
| SCHEMBL29218828 | 0.81 | EPHX2 (0.45) | HDAC8NPC1RAB9A | |
| SCHEMBL28487447 | 0.81 | EPHX2 (0.45) | HDAC8NPC1RAB9A | |
| SCHEMBL29218851 | 0.81 | POLB (0.46) | HDAC8HDAC6HDAC1ALDH1A1SYK | |
| SCHEMBL29218717 | 0.78 | EPHX1 (0.44) | ALDH1A1GAAMAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |