Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 4/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218677 | 0.85 | HDAC3 (0.39) | MAPTSYKEML4ALKNPY5R | |
| SCHEMBL29218694 | 0.82 | HDAC8 (0.41) | MAPTSYKALDH1A1FFAR4NPC1 | |
| SCHEMBL29218827 | 0.81 | SYK (0.39) | MAPTSYKALDH1A1NPC1 | |
| SCHEMBL29218599 | 0.80 | MAPT (0.48) | MAPTSYKL3MBTL1KMT2AATM | |
| SCHEMBL29218572 | 0.80 | EML4 (0.36) | MAPTSYKEML4ALKNPY5R | |
| SCHEMBL25039365 | 0.79 | KDM1A (0.42) | — | |
| SCHEMBL25042030 | 0.77 | KDM1A (0.47) | MAPTL3MBTL1KMT2AALDH1A1NPC1 | |
| SCHEMBL29218716 | 0.76 | ALDH1A1 (0.43) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29218654 | 0.76 | EPHX2 (0.33) | MAPTSYKEML4ALK | |
| SCHEMBL29218828 | 0.75 | EPHX2 (0.45) | KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |