Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17716564 | 0.82 | NPY5R (0.45) | KDM4EGAAEPHX1ROCK2ROCK1 | |
| SCHEMBL28535213 | 0.82 | KDM4E (0.55) | KDM4EGAAALDH1A1POLBHSD17B10 | |
| SCHEMBL29447185 | 0.81 | ROCK2 (0.58) | KDM4EGAAEPHX1ROCK2ROCK1 | |
| SCHEMBL9008311 | 0.81 | ROCK2 (0.58) | KDM4EGAAEPHX1ROCK2ROCK1 | |
| SCHEMBL28527735 | 0.76 | HCAR3 (0.50) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29218778 | 0.76 | TRPV1 (0.46) | KDM4EALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL25042152 | 0.76 | ROCK2 (0.51) | KDM4EGAAEPHX1ROCK2ROCK1 | |
| SCHEMBL17710614 | 0.76 | FLT3 (0.52) | KDM4EGAAEPHX1ROCK2ROCK1 | |
| SCHEMBL30279069 | 0.76 | ROCK2 (0.51) | KDM4EGAAEPHX1ROCK2ROCK1 | |
| SCHEMBL30638321 | 0.76 | FLT3 (0.52) | KDM4EGAAEPHX1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |