Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18817569 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2TSHRHTR6PSIP1CA1 | |
| SCHEMBL588340 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2TSHRHTR6PSIP1CA1 | |
| SCHEMBL27511362 | 0.84 | TSHR (0.54) | SMN1; SMN2TSHRHTR6PSIP1CA1 | |
| Phenol SCHEMBL17501495 | 0.82 | TSHR (0.52) | SMN1; SMN2TSHRHTR6PSIP1CA1 | |
| Ethylene Glycol SCHEMBL4333640 | 0.81 | TSHR (0.80) | SMN1; SMN2TSHRHTR6PSIP1CA1 | |
| Ethylene Glycol SCHEMBL4329926 | 0.81 | TSHR (0.80) | SMN1; SMN2TSHRHTR6PSIP1CA1 | |
| SCHEMBL7982393 | 0.77 | CA12 (0.56) | SMN1; SMN2TSHRCA1CA2MMP1 | |
| SCHEMBL15708959 | 0.77 | CA12 (0.56) | SMN1; SMN2TSHRCA1CA2MMP1 | |
| SCHEMBL27492965 | 0.75 | TDP1 (0.45) | SMN1; SMN2TSHRPSIP1MMP1MMP13 | |
| Benzenesulfonamide SCHEMBL8059297 | 0.74 | CA2 (0.76) | CA1CA2CA12CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897400-A | Polyethylene glycol derivative modified interleukin 12 and preparation method and application thereof | 康立泰生物医药(青岛)有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117897400-A | Polyethylene glycol derivative modified interleukin 12 and preparation method and application thereof | 康立泰生物医药(青岛)有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-115894660-B | Polyethylene glycol derivative modified interleukin 12 and preparation method and application thereof | 康立泰生物医药(青岛)有限公司 | 2024-03-15 | — | — | CN | disclosed |