SCHEMBL588340

SCHEMBL588340

O=S(O)(=S)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.62
TSHR P16473 1/20 0.62
HTR6 P50406 1/20 0.52
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
MMP2 P08253 2/20 0.48
MMP1 P03956 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
PLA2G7 Q13093 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18817569 1.00 SMN1; SMN2 (0.62) SMN1; SMN2TSHRHTR6CA1CA2
SCHEMBL27511362 0.93 TSHR (0.54) SMN1; SMN2TSHRHTR6CA1CA2
Phenol SCHEMBL17501495 0.91 TSHR (0.52) SMN1; SMN2TSHRHTR6CA1CA2
Ethylene Glycol SCHEMBL29219127 0.91 SMN1; SMN2 (0.52) SMN1; SMN2TSHRHTR6CA1CA2
SCHEMBL7982393 0.85 CA12 (0.56) SMN1; SMN2TSHRCA1CA2MMP2
SCHEMBL15708959 0.85 CA12 (0.56) SMN1; SMN2TSHRCA1CA2MMP2
Benzene SCHEMBL9751882 0.77 TSHR (1.00) SMN1; SMN2TSHRHTR6CA1CA2
SCHEMBL2818436 0.77 TSHR (0.52) SMN1; SMN2TSHRHTR6CA1CA2
SCHEMBL3409457 0.77 TSHR (1.00) SMN1; SMN2TSHRHTR6CA1CA2
SCHEMBL30812783 0.77 TSHR (1.00) SMN1; SMN2TSHRHTR6CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1993 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215019-A1 ORTHOGONAL FUNCTIONALIZATION OF BRIDGE-SUBSTITUTED BCPS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-07-03 US claimed
US-20250188142-A1 POLYETHYLENE GLYCOL DERIVATIVE MODIFIED INTERLEUKIN-12, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF KANGLITAI BIOMEDICAL (QINGDAO) CO., LTD. (CN) 2025-06-12 US claimed
CN-119040628-A Efficient green gold leaching agent and application method thereof 中南大学 2024-11-29 CN claimed
EP-4410826-A1 POLYETHYLENE GLYCOL DERIVATIVE MODIFIED INTERLEUKIN-12, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Kanglitai Biomedical (Qingdao) Co., Ltd. (CN) 2024-08-07 EP claimed
CN-118063323-A Beta-halogenated nitrate compound and preparation method and application thereof 上海师范大学 2024-05-24 CN claimed
WO-2023183757-A2 ORTHOGONAL FUNCTIONALIZATION OF BRIDGE-SUBSTITUTED BCPS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-09-28 WO claimed
CN-115986555-A Resonant cavity surface passivation film of semiconductor laser device, manufacturing method and device 深圳瑞波光电子有限公司 2023-04-18 CN claimed
CN-115894660-A Interleukin 12 modified by polyethylene glycol derivative, preparation method and application thereof 康立泰生物医药(青岛)有限公司 2023-04-04 CN claimed
CN-114539109-B Beta-ketone sulfosulfone synthesis method 成都理工大学 2022-11-25 CN claimed
CN-115024993-A Anti-saccharification sulfo composition and preparation method thereof 广州銮滢化妆品有限公司 2022-09-09 CN claimed
WO-2008101308-A1 PROCESS FOR THE PREPARATION OF 17-N-SUBSTITUTED-CARBAMOYL-4-AZA-ANDROST-1 -EN-3-ONES APOTEX PHARMACHEM INC. (CA) 2008-08-28 WO claimed
US-20070173523-A1 Process for the preparation of 17-N-substituted-carbamoyl-4-aza-androst-1-en-3-ones APOTEX PHARMACHEM INC. (CA) 2007-07-26 US claimed
US-20040106606-A1 HIV protease inhibitors BOYER FREDERICK EARL (US) 2004-06-03 US claimed
EP-1112269-A2 HIV PROTEASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2001-07-04 EP claimed
EP-0766134-B1 Solid developer-replenishing composition for processing silver halide photographic light sensitive material KONISHIROKU PHOTO IND (JP) 2000-12-13 EP claimed
WO-2000015634-A2 HIV PROTEASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2000-03-23 WO claimed
CN-1028344-C Agricultural chemical compositions TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-05-10 CN claimed
CN-1032996-A Agrochemical composition TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1989-05-24 CN claimed
EP-0183673-A1 Thiosulfonate derivatives, process for their preparation and pharmaceutical compositions containing them SANOFI (FR) 1986-06-04 EP claimed
US-4469780-A COMBINED DEVELOPMENT AND INTENSIFICATION BATH FUJI PHOTO FILM CO., LTD. (JP) 1984-09-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173523-A1 Process for the preparation of 17-N-substituted-carbamoyl-4-aza-androst-1-en-3-ones CYP17A1, CYP19A1, NR5A1 SMN1; SMN2 4281/4885TSHR 1206/4885HTR6 2131/4885
US-20250215019-A1 ORTHOGONAL FUNCTIONALIZATION OF BRIDGE-SUBSTITUTED BCPS BMP2, BMP4, DCX SMN1; SMN2 4499/4885TSHR 3699/4885HTR6 4363/4885
US-20040106606-A1 HIV protease inhibitors DNPEP, PREP, PEPD SMN1; SMN2 4359/4885TSHR 4861/4885HTR6 3296/4885
US-20250188142-A1 POLYETHYLENE GLYCOL DERIVATIVE MODIFIED INTERLEUKIN-12, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF CASP12, IL2, SUZ12 SMN1; SMN2 4356/4885TSHR 2122/4885HTR6 3226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.