Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774689 | 1.00 | LMNA (0.41) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL29220530 | 1.00 | LMNA (0.41) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL29220599 | 0.86 | APAF1 (0.49) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL29220597 | 0.86 | APAF1 (0.49) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL29220553 | 0.83 | LMNA (0.44) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL24774690 | 0.83 | LMNA (0.44) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL24774998 | 0.77 | PKM (0.42) | LMNAMEN1KMT2AAPAF1ADRB3 | |
| SCHEMBL29220560 | 0.77 | PKM (0.42) | LMNAMEN1KMT2AAPAF1ADRB3 | |
| SCHEMBL2655181 | 0.76 | AKR1C3 (0.47) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL10243646 | 0.75 | EPHX2 (0.41) | LMNATSHRMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881661-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-04-12 | — | — | CN | disclosed |