Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30198749 | 0.91 | PPARG (0.42) | RXRARXRBRXRGPPARGHSD11B1 | |
| SCHEMBL1070284 | 0.91 | PPARG (0.42) | RXRARXRBRXRGPPARGHSD11B1 | |
| SCHEMBL28978849 | 0.89 | PPARG (0.41) | RXRARXRBRXRGPPARGHSD11B1 | |
| SCHEMBL2207380 | 0.81 | ALDH1A1 (0.45) | RXRARXRBRXRGATM | |
| SCHEMBL31519054 | 0.81 | ALDH1A1 (0.45) | RXRARXRBRXRGATM | |
| SCHEMBL30586460 | 0.80 | ENPP2 (0.34) | — | |
| SCHEMBL1906335 | 0.79 | PPARG (0.42) | RXRARXRBRXRGPPARGHSD11B1 | |
| SCHEMBL30006905 | 0.79 | PPARG (0.42) | RXRARXRBRXRGPPARGHSD11B1 | |
| SCHEMBL30514778 | 0.79 | PPARG (0.35) | RXRARXRBRXRGPPARGHSD11B1 | |
| SCHEMBL28307666 | 0.79 | MRGPRX1 (0.40) | RXRARXRBRXRGPPARGHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063372-A | Preparation method of pyrrole amide compound and intermediate thereof | 年衍药业(珠海)有限公司 | 2024-05-24 | — | — | CN | disclosed |