Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25191571 | 0.89 | GPR119 (0.50) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL30234604 | 0.89 | GPR119 (0.50) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL27177244 | 0.89 | GPR119 (0.50) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL25215675 | 0.88 | USP30 (0.49) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL25917441 | 0.85 | MAPT (0.50) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL24179617 | 0.84 | ALDH1A1 (0.48) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL18361383 | 0.81 | ALDH1A1 (0.55) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL31686045 | 0.81 | ALDH1A1 (0.56) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL31686010 | 0.80 | USP30 (0.58) | GPR119ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL30089008 | 0.80 | PLA2G1B (0.51) | GPR119ALDH1A1MAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119629-A | Nitrogen-containing heterocyclic compound and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-31 | — | — | CN | disclosed |