Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25215675 | 0.91 | USP30 (0.49) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL31686045 | 0.88 | ALDH1A1 (0.56) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL27177190 | 0.83 | PLA2G1B (0.51) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL30089008 | 0.83 | PLA2G1B (0.51) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL27177244 | 0.83 | GPR119 (0.50) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL29220856 | 0.80 | GPR119 (0.48) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL6210547 | 0.80 | ALDH1A1 (0.67) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL29148533 | 0.80 | USP30 (0.48) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL30849217 | 0.80 | USP30 (0.48) | USP30ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL29148532 | 0.80 | USP30 (0.48) | USP30ALDH1A1MAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289814-A1 | COMPOUNDS AS PARP1 INHIBITIORS | NINGBO NEWBAY TECH DEVELOPMENT CO LTD (CN) | 2025-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289814-A1 | COMPOUNDS AS PARP1 INHIBITIORS | PARP1, PARP11, PARP12 | USP30 1745/4885ALDH1A1 434/4885MAPT 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.