Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220941 | 0.92 | USP30 (0.46) | USP30DDB1CRBNMEN1MAPT | |
| SCHEMBL29220893 | 0.92 | USP30 (0.49) | USP30DDB1CRBNMEN1MAPT | |
| SCHEMBL25093627 | 0.84 | DDB1 (0.58) | USP30DDB1CRBNMEN1MAPT | |
| SCHEMBL21063452 | 0.80 | GPR119 (0.52) | USP30DDB1CRBNMEN1MAPT | |
| SCHEMBL25738320 | 0.80 | PARP1 (0.47) | USP30MEN1MAPTTSHRKMT2A | |
| SCHEMBL31048020 | 0.80 | MEN1 (0.45) | USP30MEN1MAPTTSHRKMT2A | |
| SCHEMBL31178523 | 0.79 | PARP1 (0.48) | USP30MEN1MAPTTSHRKMT2A | |
| SCHEMBL25093965 | 0.79 | PARP1 (0.48) | USP30MEN1MAPTTSHRKMT2A | |
| Lithium Ion SCHEMBL21063388 | 0.78 | DDB1 (0.44) | USP30DDB1CRBNKMT2ASMN1; SMN2 | |
| SCHEMBL25215675 | 0.77 | USP30 (0.49) | USP30DDB1CRBNMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119629-A | Nitrogen-containing heterocyclic compound and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-31 | — | — | CN | disclosed |