Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954344 | 1.00 | MAPT (0.50) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL1030553 | 0.86 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL30114672 | 0.86 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL7012337 | 0.84 | MAPT (0.48) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL17707775 | 0.83 | TSHR (0.53) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL6656676 | 0.82 | MEN1 (0.68) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL18285205 | 0.82 | TSHR (0.56) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL4378724 | 0.82 | NR1D1 (0.39) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL7006308 | 0.82 | MAPT (0.46) | MAPTMEN1KMT2AMAPK1TSHR | |
| SCHEMBL3789796 | 0.81 | ALDH1A1 (0.64) | MAPTMEN1KMT2AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084772-A | Nilapatinib intermediate, preparation method and method for preparing Nilapatinib by using same | 重庆博腾制药科技股份有限公司 | 2024-05-28 | — | — | CN | disclosed |