SCHEMBL29221815

SCHEMBL29221815

CN(C)c1ccc(CNC(=O)N(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.61
MEN1 O00255 3/20 0.61
ALDH1A1 P00352 9/20 0.50
KDM4E B2RXH2 5/20 0.50
EPHX2 P34913 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HTT P42858 1/20 0.50
GAA P10253 2/20 0.49
HPGD P15428 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 1/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
GFER P55789 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29221790 0.87 ALDH1A1 (0.62) KMT2AMEN1ALDH1A1EPHX2NPSR1
SCHEMBL29221795 0.85 SMN1; SMN2 (0.66) KMT2AMEN1ALDH1A1NPSR1HTT
SCHEMBL29221809 0.82 KDM4E (0.56) KMT2AMEN1ALDH1A1KDM4ENPSR1
SCHEMBL29221798 0.82 L3MBTL1 (0.60) KMT2AMEN1ALDH1A1NPSR1GAA
SCHEMBL22560026 0.81 LMNA (0.62) KMT2AMEN1ALDH1A1NPSR1GAA
SCHEMBL29221787 0.81 NPC1 (0.63) KMT2AMEN1ALDH1A1NPSR1HTT
SCHEMBL29221799 0.81 ALDH1A1 (0.60) KMT2AMEN1ALDH1A1KDM4ENPSR1
SCHEMBL5160351 0.81 EPHX2 (0.46) KMT2AMEN1ALDH1A1KDM4EEPHX2
SCHEMBL29221810 0.79 SMN1; SMN2 (0.57) KMT2AMEN1ALDH1A1KDM4ENPSR1
SCHEMBL13911219 0.79 HDAC1 (0.51) ALDH1A1KDM4EEPHX2NPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886718-B Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound 内蒙古工业大学 2024-05-24 CN disclosed
CN-117886718-A Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound 内蒙古工业大学 2024-04-16 CN disclosed