Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221823 | 0.89 | HDAC4 (0.46) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL29222298 | 0.81 | TAS1R3 (0.43) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL29221831 | 0.78 | ALDH1A1 (0.41) | RAB9ALMNAHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL2747398 | 0.74 | HDAC1 (0.66) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL13290003 | 0.74 | HDAC1 (0.66) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL7729352 | 0.73 | HDAC1 (0.74) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL29221828 | 0.73 | GCG (0.46) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL12890752 | 0.73 | HDAC4 (0.57) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL13290360 | 0.72 | HDAC1 (0.66) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL30858818 | 0.72 | HDAC1 (0.65) | HDAC1HDAC4HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886748-A | Quinoline amino acid conjugate and preparation method and application thereof | 天津科技大学 | 2024-04-16 | — | — | CN | disclosed |