Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 6/20 | 0.44 |
| ▸ | GSK3B | P49841 | 6/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29222056 | 0.85 | GSK3A (0.58) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL29222279 | 0.81 | NR3C1 (0.49) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL29222037 | 0.80 | CDK5 (0.58) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL29222099 | 0.76 | GSK3B (0.59) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL29222046 | 0.76 | GSK3A (0.59) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| Indoxyl Red SCHEMBL22890564 | 0.74 | S100A4 (0.71) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| Indoxyl Red SCHEMBL30636774 | 0.74 | S100A4 (0.71) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL30319777 | 0.73 | GSK3A (0.74) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL28426927 | 0.70 | CDK2 (0.53) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL29941741 | 0.69 | AR (0.54) | ARAHRDYRK1AFLT3NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125960-A | Bisindole 3-ketone compound, application and preparation method thereof | 云南农业大学 | 2024-06-04 | — | — | CN | disclosed |