Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | HTR2B | P41595 | 4/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348107 | 0.92 | HTR1A (0.60) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| SCHEMBL140310 | 0.85 | HDAC3 (0.56) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| SCHEMBL10514635 | 0.81 | HDAC3 (0.54) | HDAC3HDAC1HDAC8NCOR2DRD2 | |
| SCHEMBL3891857 | 0.80 | HDAC3 (0.68) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| Hydrochloric Acid SCHEMBL4251907 | 0.79 | HDAC3 (0.67) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| SCHEMBL4229925 | 0.79 | HTR7 (0.73) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| SCHEMBL4225894 | 0.78 | HDAC3 (0.71) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| Hydrochloric Acid SCHEMBL4222979 | 0.78 | HTR7 (0.71) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| SCHEMBL141699 | 0.77 | MAOB (0.61) | HDAC3HDAC1HDAC8NCOR2HTR1A | |
| SCHEMBL11689265 | 0.77 | HDAC8 (0.38) | HDAC3HDAC1HDAC8NCOR2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642397-A | Modified proteins and protein binders | 上海睿跃生物科技有限公司 | 2024-03-01 | — | — | CN | disclosed |