Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141699 | 0.92 | MAOB (0.61) | HDAC3HDAC1HDAC8NCOR2MAOB | |
| SCHEMBL27617685 | 0.89 | SLC18A3 (0.56) | HDAC3HDAC1HDAC8NCOR2MAOB | |
| SCHEMBL10514635 | 0.86 | HDAC3 (0.54) | HDAC3HDAC1HDAC8NCOR2MAOB | |
| SCHEMBL29223993 | 0.85 | HDAC3 (0.56) | HDAC3HDAC1HDAC8NCOR2DRD2 | |
| SCHEMBL27593297 | 0.82 | NR1H2 (0.49) | MAOBDRD2DRD3SLC18A3KDM4E | |
| SCHEMBL10090165 | 0.80 | MEN1 (0.62) | MAOBDRD2HTR1AHTR2AHTR7 | |
| SCHEMBL29865235 | 0.80 | MEN1 (0.62) | MAOBDRD2HTR1AHTR2AHTR7 | |
| Acetic Acid SCHEMBL6524206 | 0.79 | DRD2 (0.59) | HDAC3HDAC1HDAC8NCOR2MAOB | |
| SCHEMBL7276869 | 0.77 | HDAC3 (0.60) | HDAC3HDAC1HDAC8NCOR2DRD2 | |
| SCHEMBL28348107 | 0.77 | HTR1A (0.60) | HDAC3HDAC1HDAC8NCOR2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274056-B1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOCHINOLINIUM DERIVATIVES, SPECIFIC ALKANOLAMINES AND HYDROGEN PEROXYDE | HENKEL AG & CO KGAA (DE) | 2012-10-03 | — | — | EP | claimed |
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | GROSS WIBKE | 2011-06-23 | — | — | US | claimed |
| US-20110056508-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | GROSS WIBKE | 2011-03-10 | — | — | US | claimed |
| US-9693937-B2 | Foil applicator | HENKEL AG & CO. KGAA (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20150174019-A1 | FOIL APPLICATOR | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20120055500-A1 | Foil Applicator | HENKEL AG & CO. KGAA (DE) | 2012-03-08 | — | — | US | disclosed |
| US-8025704-B2 | Matting additive for blond hair dyeing | HENKEL AG & CO. KGAA (DE) | 2011-09-27 | — | — | US | disclosed |
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | GROSS WIBKE | 2011-06-23 | — | — | US | disclosed |
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | MANNECK HARTMUT | 2011-06-02 | — | — | US | disclosed |
| US-20110056508-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | GROSS WIBKE | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | LDHB, HMBS, HBB | HDAC3 1280/4885HDAC1 781/4885HDAC8 506/4885 |
| US-20110056508-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | KRT18, H1-3, H1-2 | HDAC3 95/4885HDAC1 173/4885HDAC8 407/4885 |
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | KRT18, QDPR, DSG1 | HDAC3 252/4885HDAC1 214/4885HDAC8 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.