Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463566 | 1.00 | MAOB (0.49) | MAOBMAOAPDE4DALOX5MEN1 | |
| SCHEMBL5030486 | 0.73 | MAOB (0.62) | MAOBMAOAPDE4DALOX5MEN1 | |
| SCHEMBL29225183 | 0.72 | MAOB (0.49) | MAOBMAOAPDE4DALOX5MEN1 | |
| SCHEMBL30463541 | 0.72 | MAOB (0.49) | MAOBMAOAPDE4DALOX5MEN1 | |
| SCHEMBL5061307 | 0.72 | MAOB (0.49) | MAOBMAOAPDE4DMEN1KMT2A | |
| SCHEMBL12854020 | 0.72 | MAOB (0.71) | MAOBMAOAALOX5MEN1KMT2A | |
| SCHEMBL61411 | 0.72 | MAOB (0.71) | MAOBMAOAALOX5MEN1KMT2A | |
| SCHEMBL103158 | 0.71 | MAOB (0.63) | MAOBMAOAALOX5TDP1ADRA2A | |
| SCHEMBL30036439 | 0.71 | MAOB (0.63) | MAOBMAOAALOX5TDP1ADRA2A | |
| SCHEMBL1110879 | 0.70 | LMNA (0.64) | MAOBMAOAPDE4DALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |