Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110879 | 0.85 | LMNA (0.64) | MAOBMAOAALOX5MEN1KMT2A | |
| SCHEMBL12854020 | 0.84 | MAOB (0.71) | MAOBMAOAALOX5MEN1KMT2A | |
| SCHEMBL61411 | 0.84 | MAOB (0.71) | MAOBMAOAALOX5MEN1KMT2A | |
| SCHEMBL13522927 | 0.83 | NPC1 (0.60) | MAOBMAOAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2958058 | 0.81 | AKR1C3 (0.52) | MAOBMAOAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30036439 | 0.79 | MAOB (0.63) | MAOBMAOAALOX5CYP2D6MAPT | |
| SCHEMBL103158 | 0.79 | MAOB (0.63) | MAOBMAOAALOX5CYP2D6MAPT | |
| SCHEMBL19497662 | 0.78 | MAOB (0.63) | MAOBMAOAALOX5MEN1KMT2A | |
| SCHEMBL9812762 | 0.77 | MAOB (0.62) | MAOBMAOAALOX5MEN1KMT2A | |
| SCHEMBL20174691 | 0.77 | MAOB (1.00) | MAOBMAOAALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689732-A4 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | UNIV NORTH CAROLINA (US) | 2008-10-22 | — | — | EP | claimed |
| EP-1689732-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | The University of North Carolina at Chapel Hill (US) | 2006-08-16 | — | — | EP | claimed |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | TIDWELL RICHARD R (US) | 2005-09-08 | — | — | US | claimed |
| WO-2005055935-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-06-23 | — | — | WO | claimed |
| US-4054551-A | Benzofuranylphenol stabilizers | THE B. F. GOODRICH COMPANY (US) | 1977-10-18 | — | — | US | claimed |
| CN-107698571-A | Naphthalimide-coumarin DNA targeting double-intercalator, synthesis and application thereof | 大连理工大学 | 2018-02-16 | — | — | CN | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| EP-1689732-A4 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | UNIV NORTH CAROLINA (US) | 2008-10-22 | — | — | EP | disclosed |
| US-20080221191-A1 | Cationic substituted benzofurans as antimicrobial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-11 | — | — | US | disclosed |
| US-7417158-B2 | Mycobacterium tuberculosis infection; protozoan pathogens; fungal pathogens | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-08-26 | — | — | US | disclosed |
| US-20080114047-A1 | Cationic substituted benzofurans as antimicrobial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-05-15 | — | — | US | disclosed |
| US-4304712-A | CONSTRUCTION MATERIALS | THE B. F. GOODRICH COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| US-4133799-A | Benzofuranylphenol stabilizers | THE B. F. GOODRICH COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133799-A | Benzofuranylphenol stabilizers | THE B. F. GOODRICH COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133799-A | Benzofuranylphenol stabilizers | THE B. F. GOODRICH COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4054551-A | Benzofuranylphenol stabilizers | THE B. F. GOODRICH COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054551-A | Benzofuranylphenol stabilizers | THE B. F. GOODRICH COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054551-A | Benzofuranylphenol stabilizers | THE B. F. GOODRICH COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114047-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | MAOB 2348/4885MAOA 2700/4885AKR1C3 2985/4885 |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | MAOB 2348/4885MAOA 2700/4885AKR1C3 2985/4885 |
| US-20080221191-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | MAOB 2348/4885MAOA 2700/4885AKR1C3 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.