Fluorene

Fluorene

SCHEMBL29225375

C=C(C)C(=O)O.C=C(C)C(=O)O.Cc1cccc(O)c1C.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.49
ATM Q13315 1/20 0.49
SRD5A2 P31213 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAOA P21397 2/20 0.40
CYP1A2 P05177 1/20 0.40
ADRA2A P08913 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2C P28335 1/20 0.40
SLC6A4 P31645 1/20 0.40
HTR2B P41595 1/20 0.40
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL27623343 0.86 TRPA1 (0.65) TRPA1ATMSRD5A2NPC1RAB9A
Fluorene SCHEMBL2127827 0.84 SRD5A2 (0.53) SRD5A2NPC1RAB9AMAOACYP1A2
Fluorene SCHEMBL1151459 0.84 SRD5A2 (0.53) SRD5A2NPC1RAB9AMAOACYP1A2
Fluorene SCHEMBL29848606 0.84 SRD5A2 (0.53) SRD5A2NPC1RAB9AMAOACYP1A2
Fluorene SCHEMBL4600798 0.82 SRD5A2 (0.47) SRD5A2NPC1RAB9AMAOACYP1A2
Fluorene SCHEMBL28045968 0.82 SRD5A2 (0.47) SRD5A2NPC1RAB9AMAOACYP1A2
Methacrylic Acid SCHEMBL28201576 0.79 TRPA1 (0.55) TRPA1ATMNPC1RAB9ACYP1A2
Fluorene SCHEMBL21084447 0.79 SRD5A2 (0.47) SRD5A2NPC1RAB9AMAOACYP1A2
Orthocresol SCHEMBL17842626 0.76 TRPA1 (0.41) TRPA1ATMCYP1A2TSHRHSD17B10
Fluorene SCHEMBL2784787 0.76 TRPA1 (0.46) TRPA1ATMSRD5A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117916664-A Photosensitive composition, cured product, and organic EL display device 东丽株式会社 2024-04-19 CN disclosed