Methacrylic Acid

Methacrylic Acid

SCHEMBL28201576

C=C(C)C(=O)O.CC(C)=O.Cc1cccc(O)c1C.OCCO

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.55
ATM Q13315 1/20 0.55
HSD17B10 Q99714 3/20 0.38
TP53 P04637 2/20 0.38
LMNA P02545 2/20 0.38
NPC1 O15118 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
THRB P10828 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27795156 0.85 ALDH1A1 (0.50) TRPA1HSD17B10NPC1HTTRAB9A
O-Xylene SCHEMBL28201006 0.83 ERCC5 (0.42) TSHRHTTALDH1A1KDM4EHPGD
Oxalic Acid SCHEMBL28473849 0.80 TRPA1 (0.77) TRPA1ATMHSD17B10TP53LMNA
Acetic Acid SCHEMBL28437480 0.80 TRPA1 (0.77) TRPA1ATMHSD17B10TP53LMNA
Fluorene SCHEMBL29225375 0.79 TRPA1 (0.49) TRPA1ATMHSD17B10TP53LMNA
Orthocresol SCHEMBL27875890 0.79 CTBP2 (0.38) TRPA1ATMHSD17B10LMNAHTT
Bicarbonate SCHEMBL27605791 0.78 TRPA1 (0.81) TRPA1ATMHSD17B10TP53LMNA
Phenol SCHEMBL2885488 0.78 TRPA1 (0.65) TRPA1ATMHSD17B10TP53LMNA
Orthocresol SCHEMBL17842626 0.77 TRPA1 (0.41) TRPA1ATMHSD17B10LMNATSHR
Methacrylic Acid SCHEMBL27824598 0.77 ALDH1A1 (0.58) TRPA1ATMHSD17B10NPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107722181-A It is chemically crosslinked the preparation method of nanometer composite epoxy resin 成都昂多生物技术有限责任公司 2018-02-23 CN disclosed