SCHEMBL29225701

SCHEMBL29225701

C=C(CNCCc1ccc(O)c(O)c1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.51
▸ HSD17B10 Q99714 4/20 0.51
▸ KDM4E B2RXH2 4/20 0.51
▸ HIF1A Q16665 3/20 0.51
▸ ALDH1A1 P00352 3/20 0.51
▸ LMNA P02545 3/20 0.51
▸ BLM P54132 3/20 0.51
▸ HPGD P15428 2/20 0.51
▸ PTGS1 P23219 2/20 0.51
▸ MAPK1 P28482 3/20 0.49
▸ ALOX15 P16050 3/20 0.49
▸ TP53 P04637 2/20 0.49
▸ THPO P40225 2/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ TSHR P16473 1/20 0.49
▸ NFKB1 P19838 1/20 0.49
▸ DRD1 P21728 4/20 0.48
▸ DRD3 P35462 4/20 0.48
▸ ADRB2 P07550 3/20 0.48
▸ SLC6A2 P23975 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28773631 0.87 MAPT (0.53) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL29777347 0.80 MAPT (0.58) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL11017571 0.80 MAPT (0.58) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL29997235 0.80 IAPP (0.56) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL1655398 0.80 IAPP (0.56) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL28431834 0.78 MAPT (0.59) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL26292973 0.78 MAPT (0.66) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL30088530 0.77 DRD1 (0.71) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL11806768 0.77 DRD1 (0.71) MAPTHSD17B10KDM4EHIF1AALDH1A1
SCHEMBL11074753 0.76 MAPT (0.63) MAPTHSD17B10KDM4EHIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3593127-B1 MICROFLUIDIC DEVICE EPIGEM LTD (GB) 2024-12-18 — — EP claimed
EP-3732263-B1 ADHESIVE COMPOSITIONS BASED ON BIOMIMETIC COPOLYMER SYSTEMS WITH INCREASED TOUGHNESS PURDUE RESEARCH FOUNDATION (US) 2022-08-10 — — EP claimed
EP-4734929-A1 SYSTEM AND METHODS FOR MODIFYING SURFACE PROPERTIES OF KERATIN-CONTAINING SURFACES Edulis Labs Inc. (US) 2026-05-06 — — EP disclosed
WO-2025006080-A1 SYSTEM AND METHODS FOR MODIFYING SURFACE PROPERTIES OF KERATIN-CONTAINING SURFACES EDULIS LABS INC. (US) 2025-01-02 — — WO disclosed
US-20240246036-A1 ANTIFOULING MEMBRANES, FILTRATION SYSTEMS, AND RELATED ASPECTS FOR CONTINUOUS MOLECULAR HARVESTING AND OTHER APPLICATIONS THE JOHNS HOPKINS UNIVERSITY 2024-07-25 — — US disclosed
CN-114106361-B Polypropylene material loaded with zwitterionic polymer coating and preparation method thereof 苏州至善新材料科技有限公司 2024-04-05 — — CN disclosed
CN-114010510-B Dentin bonding pretreatment composition based on DMA (direct memory access) and application thereof 中国人民解放军总医院第一医学中心 2023-05-05 — — CN disclosed
US-20220400686-A1 COMPOSITIONS AND METHODS FOR ON-DEMAND RELEASE OF ANTIMICROBIAL AGENTS UNIVERSITY OF MASSACHUSETTS 2022-12-22 — — US disclosed
EP-4069712-A1 COMPOSITIONS AND METHODS FOR ON-DEMAND RELEASE OF ANTIMICROBIAL AGENTS University of Massachusetts (US) 2022-10-12 — — EP disclosed
CN-110724426-B Carboxylic betaine zwitterionic composite antibacterial functional coating material and preparation method and application thereof 江南大学 2022-05-13 — — CN disclosed
CN-114010510-A Dentin bonding pretreatment composition based on DMA (direct memory access) and application thereof 中国人民解放军总医院第一医学中心 2022-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220400686-A1 COMPOSITIONS AND METHODS FOR ON-DEMAND RELEASE OF ANTIMICROBIAL AGENTS CGAS, ARG1, CUTA MAPT 4747/4885HSD17B10 3640/4885KDM4E 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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