SCHEMBL1655398

SCHEMBL1655398

C=C(CCc1ccc(O)c(O)c1)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IAPP P10997 3/20 0.56
▸ APP P05067 2/20 0.53
▸ CYP19A1 P11511 1/20 0.53
▸ TYR P14679 1/20 0.53
▸ KDM4E B2RXH2 5/20 0.52
▸ MAPT P10636 5/20 0.52
▸ TDP1 Q9NUW8 3/20 0.52
▸ ALDH1A1 P00352 3/20 0.52
▸ HIF1A Q16665 3/20 0.52
▸ HSD17B10 Q99714 3/20 0.52
▸ ADRA2A P08913 2/20 0.52
▸ DRD2 P14416 2/20 0.52
▸ ALOX15 P16050 2/20 0.52
▸ DRD1 P21728 2/20 0.52
▸ DRD4 P21917 2/20 0.52
▸ DRD5 P21918 2/20 0.52
▸ SLC6A2 P23975 2/20 0.52
▸ MAPK1 P28482 2/20 0.52
▸ DRD3 P35462 2/20 0.52
▸ RECQL P46063 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29997235 1.00 IAPP (0.56) IAPPAPPCYP19A1TYRKDM4E
Dopamine SCHEMBL28568506 0.94 MAPK1 (0.64) IAPPAPPCYP19A1TYRKDM4E
SCHEMBL3383712 0.84 IAPP (0.57) IAPPAPPCYP19A1TYRKDM4E
SCHEMBL13636197 0.82 ALOX15 (0.59) IAPPAPPCYP19A1TYRKDM4E
SCHEMBL925636 0.82 IAPP (0.62) IAPPAPPCYP19A1TYRKDM4E
SCHEMBL30986806 0.82 IAPP (0.62) IAPPAPPCYP19A1TYRKDM4E
Hydrochloric Acid SCHEMBL10340417 0.80 IAPP (0.61) IAPPAPPCYP19A1TYRKDM4E
SCHEMBL7055265 0.80 CA2 (0.48) CYP19A1KDM4EMAPTTDP1ALDH1A1
SCHEMBL29225701 0.80 MAPT (0.51) APPKDM4EMAPTTDP1ALDH1A1
Dopamine SCHEMBL9051903 0.78 KDM4E (0.84) IAPPKDM4EMAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215432-B Granular sludge suitable for town sewage treatment and rapid generation method thereof 同济大学 2023-07-21 — — CN claimed
CN-115215432-A Granular sludge suitable for town sewage treatment and rapid generation method thereof 同济大学 2022-10-21 — — CN claimed
CN-112221476-A Mussel bionic modified polyurethane sponge multifunctional adsorbent, preparation method and application thereof 四川大学 2021-01-15 — — CN claimed
CN-110183902-A A kind of aqueous intaglio printing ink and its preparation method and application 云浮市金莱昊化工有限公司 2019-08-30 — — CN claimed
CN-115215432-B Granular sludge suitable for town sewage treatment and rapid generation method thereof 同济大学 2023-07-21 — — CN disclosed
CN-115215432-A Granular sludge suitable for town sewage treatment and rapid generation method thereof 同济大学 2022-10-21 — — CN disclosed
CN-109054101-B Super-hydrophobic magnetic nanocellulose and preparation method thereof 福建农林大学 2021-04-09 — — CN disclosed
CN-107532050-B Pressure sensitive adhesive for transdermal drug delivery 诺芬药品公司 2021-03-02 — — CN disclosed
CN-112221476-A Mussel bionic modified polyurethane sponge multifunctional adsorbent, preparation method and application thereof 四川大学 2021-01-15 — — CN disclosed
EP-2490727-B1 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE BIOMEDICAL BONDING AB (SE) 2020-09-23 — — EP disclosed
US-10406116-B2 Pressure-sensitive adhesives for transdermal drug delivery NOVEN PHARMACEUTICALS, INC. (US) 2019-09-10 — — US disclosed
US-20180116699-A1 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE BIOMEDICAL BONDING AB (SE) 2018-05-03 — — US disclosed
CN-107532050-A Contact adhesive for cutaneous penetration 诺芬药品公司 2018-01-02 — — CN disclosed
US-20160374954-A1 PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2016-12-29 — — US disclosed
WO-2016127020-A1 PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2016-08-11 — — WO disclosed
US-20160000484-A1 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE REPAIR TECHNOLOGIES SWEDEN AB (SE) 2016-01-07 — — US disclosed
US-20120308532-A1 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE PROPPABORT AB (SE) 2012-12-06 — — US disclosed
EP-2490727-A2 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE Repair Technologies Sweden AB (SE) 2012-08-29 — — EP disclosed
WO-2011048077-A2 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE REPAIR TECHNOLOGIES SWEDEN AB (SE) 2011-04-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120308532-A1 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE VCL, BMP2, SHC1 IAPP 2250/4885APP 260/4885CYP19A1 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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