Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28842281 | 0.84 | PPARG (0.44) | INSRIGF1RCYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL10687082 | 0.82 | NQO1 (0.58) | NQO1INSRIGF1RKMT2AALDH1A1 | |
| SCHEMBL27673460 | 0.81 | INSR (0.49) | NQO1INSRIGF1RCYP3A4KMT2A | |
| SCHEMBL8111501 | 0.77 | LMNA (0.55) | CYP3A4ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL1276647 | 0.77 | INSR (0.46) | NQO1INSRIGF1RCYP3A4KMT2A | |
| SCHEMBL30402519 | 0.76 | MEN1 (0.51) | NQO1CYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL1852524 | 0.76 | MEN1 (0.51) | NQO1CYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL1855445 | 0.74 | LMNA (0.62) | CYP3A4KMT2AMEN1GAPDHALDH1A1 | |
| SCHEMBL10054017 | 0.72 | ELANE (0.43) | NQO1INSRIGF1RCYP3A4KMT2A | |
| SCHEMBL9153664 | 0.72 | INSR (0.48) | INSRIGF1RCYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924306-A | Full-synthesis preparation method of wedelolactone or demethylwedelolactone | 中国药科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117924306-A | Full-synthesis preparation method of wedelolactone or demethylwedelolactone | 中国药科大学 | 2024-04-26 | — | — | CN | disclosed |