Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | GAPDH | P04406 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876644 | 0.91 | KMT2A (0.62) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL2900297 | 0.91 | LMNA (0.60) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL26500688 | 0.87 | SMN1; SMN2 (0.55) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL12216190 | 0.87 | KMT2A (0.56) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL4758947 | 0.86 | LMNA (0.65) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL14959931 | 0.86 | KDM4E (0.61) | LMNAGAAALDH1A1KMT2APOLB | |
| SCHEMBL14959934 | 0.86 | KDM4E (0.61) | LMNAGAAALDH1A1KMT2APOLB | |
| SCHEMBL27663537 | 0.85 | LMNA (0.52) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL7074846 | 0.85 | LMNA (0.60) | LMNAGAAALDH1A1KMT2AALOX15 | |
| SCHEMBL27598271 | 0.85 | LMNA (0.59) | LMNAGAAALDH1A1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563301-A | Synthesis process of 3, 4-methylenedioxyphenol | 绵阳三香汇生物科技有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-106432542-A | Preparation and application of O-3, 4-methylenedioxy phenylacetate-N-trimethylchitosan quaternary ammonium salt | 湖南工业大学 | 2017-02-22 | — | — | CN | claimed |
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | INVASC THERAPEUTICS, INC. (US) | 2013-06-20 | — | — | US | claimed |
| US-8198317-B2 | Methylenedioxy phenolic compounds and their use to treat disease | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | claimed |
| CN-102149702-A | Novel methylenedioxy phenolic compounds and their use to treat disease | UNIV OHIO STATE RES FOUND | 2011-08-10 | — | — | CN | claimed |
| EP-2324005-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | The Ohio State University Research Foundation (US) | 2011-05-25 | — | — | EP | claimed |
| WO-2010017323-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | WO | claimed |
| US-20100035849-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | US | claimed |
| US-11804602-B2 | Negative electrode for lithium ion secondary battery, and lithium ion secondary battery including same | HONDA MOTOR CO., LTD. (JP) | 2023-10-31 | — | — | US | disclosed |
| US-20230039319-A1 | DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES | DHANOA DALJIT SINGH (US) | 2023-02-09 | — | — | US | disclosed |
| CN-113563301-A | Synthesis process of 3, 4-methylenedioxyphenol | 绵阳三香汇生物科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113563301-A | Synthesis process of 3, 4-methylenedioxyphenol | 绵阳三香汇生物科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-20210305572-A1 | NEGATIVE ELECTRODE FOR LITHIUM ION SECONDARY BATTERY, AND LITHIUM ION SECONDARY BATTERY INCLUDING SAME | HONDA MOTOR CO., LTD. (JP) | 2021-09-30 | — | — | US | disclosed |
| EP-3848367-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |
| WO-2010017323-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20090170835-A1 | ISOINDOLINE DERIVATIVES | MARUISHI PHARMACEUTICAL CO., LTD. | 2009-07-02 | — | — | US | disclosed |
| US-7521451-B2 | Isoindoline derivative | MARUISHI PHARMACEUTICAL CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| CN-1608061-A | Therapeutic isoquinoline compounds | ASTRAZENECA AB (SE) | 2005-04-20 | — | — | CN | disclosed |
| CN-1142822-A | Cyclic amide derivatives as neurokinin A antagonists | ZENECA LTD (GB) | 1997-02-12 | — | — | CN | disclosed |
| EP-0003670-A1 | Preparation of alkyl 2-aryl acrylates | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1979-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039319-A1 | DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES | AGTR2, AGTR1, EDNRA | LMNA 1922/4885GAA 1263/4885ALDH1A1 2247/4885 |
| US-20100035849-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | REN, PCSK9, ALOX12 | LMNA 1396/4885GAA 889/4885ALDH1A1 787/4885 |
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | REN, PCSK9, COMT | LMNA 845/4885GAA 603/4885ALDH1A1 773/4885 |
| US-20090170835-A1 | ISOINDOLINE DERIVATIVES | OPRD1, OPRK1, OPRL1 | LMNA 3803/4885GAA 4640/4885ALDH1A1 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.