SCHEMBL29226752

SCHEMBL29226752

CC(C)(C=O)C1CCN(C(F)C(F)F)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29226646 0.82
SCHEMBL18285482 0.72 NCF1 (0.33)
SCHEMBL29226645 0.71
SCHEMBL30980356 0.71
SCHEMBL25025564 0.68 KDM1A (0.33)
SCHEMBL3271093 0.67 ADH1A (0.32)
SCHEMBL4471405 0.67 CYP2D6 (0.38)
SCHEMBL3276795 0.65 ADH1A (0.36)
SCHEMBL10012993 0.63
SCHEMBL28968115 0.63 GPR119 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119595-A Compounds and compositions for the treatment of diseases associated with STING activity 艾福姆德尤股份有限公司 2024-05-31 CN disclosed