Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227135 | 0.94 | LMNA (0.58) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227112 | 0.87 | LMNA (0.60) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227117 | 0.86 | LMNA (0.59) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227251 | 0.85 | MC4R (0.51) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL30873550 | 0.84 | LMNA (0.57) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227161 | 0.83 | LMNA (0.52) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227359 | 0.83 | LMNA (0.45) | MC4RLMNAMEN1KMT2A | |
| SCHEMBL29227120 | 0.83 | PRMT5 (0.53) | MC4RLMNAMEN1KMT2A | |
| SCHEMBL29227101 | 0.82 | LMNA (0.55) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227088 | 0.82 | LMNA (0.55) | MC4RLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |