Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873571 | 0.91 | HRH3 (0.53) | HRH3HTR2AHTR7HTR6MAPT | |
| SCHEMBL29227135 | 0.90 | LMNA (0.58) | LMNAKDM4EMEN1KMT2AMC4R | |
| SCHEMBL29227088 | 0.89 | LMNA (0.55) | LMNAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL29227101 | 0.87 | LMNA (0.55) | LMNAKDM4EMEN1KMT2AHRH3 | |
| SCHEMBL29227118 | 0.85 | LMNA (0.51) | LMNAKDM4EMEN1KMT2AMC4R | |
| SCHEMBL29227124 | 0.84 | MC4R (0.61) | LMNAKDM4EMEN1KMT2AMC4R | |
| SCHEMBL30873570 | 0.79 | LMNA (0.65) | LMNAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29227359 | 0.79 | LMNA (0.45) | LMNAMEN1KMT2AMC4R | |
| SCHEMBL29227120 | 0.79 | PRMT5 (0.53) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29227158 | 0.77 | LMNA (0.62) | LMNAKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |