Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227161 | 0.94 | LMNA (0.52) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227249 | 0.90 | HRH3 (0.48) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227144 | 0.89 | LMNA (0.45) | MC4RLMNA | |
| SCHEMBL29227129 | 0.89 | LMNA (0.49) | MC4RLMNA | |
| SCHEMBL29227194 | 0.89 | DRD2 (0.51) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227384 | 0.86 | ABCB1 (0.46) | MC4RLMNA | |
| SCHEMBL29227124 | 0.85 | MC4R (0.61) | MC4RLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29227170 | 0.83 | ALDH1A1 (0.44) | MC4R | |
| SCHEMBL30873534 | 0.83 | ALDH1A1 (0.44) | MC4R | |
| SCHEMBL29227135 | 0.83 | LMNA (0.58) | MC4RLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |