Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819820 | 0.88 | MAPT (0.56) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13581060 | 0.88 | CCR5 (0.49) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29227165 | 0.86 | CYP19A1 (0.56) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25823927 | 0.84 | CCR5 (0.46) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31215857 | 0.84 | CCR5 (0.46) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29227222 | 0.84 | CCR5 (0.57) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29151250 | 0.84 | RXRA (0.56) | MAPTNPC1RAB9ASMN1; SMN2MAOA | |
| SCHEMBL6927459 | 0.84 | CYP19A1 (0.57) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6926436 | 0.83 | MAPT (0.62) | CCR5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29074783 | 0.82 | PTPN1 (0.50) | CCR5MAPTMAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |