Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935287 | 0.85 | KMT2A (0.41) | KMT2AMEN1ATMRAB9ANPC1 | |
| SCHEMBL16470252 | 0.78 | MEN1 (0.42) | KMT2AMEN1ATMRAB9ANPC1 | |
| SCHEMBL12075024 | 0.74 | MEN1 (0.39) | KMT2AMEN1ATMRAB9ANPC1 | |
| SCHEMBL17193116 | 0.72 | TERT (0.44) | KMT2AMEN1ATMRAB9ANPC1 | |
| Bromide SCHEMBL5255425 | 0.72 | KMT2A (0.71) | KMT2AMEN1ATMKDM4ESMN1; SMN2 | |
| SCHEMBL2796407 | 0.71 | ATM (0.50) | KMT2AMEN1ATMRAB9ANPC1 | |
| 1-Ethylquinolonium SCHEMBL309459 | 0.70 | ACHE (0.63) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL5801180 | 0.69 | KDM4E (0.53) | KMT2AMEN1RAB9ANPC1KDM4E | |
| 1-Ethylquinolonium SCHEMBL10655763 | 0.68 | ACHE (0.64) | ACHEBCHE | |
| 1-Ethylquinolonium SCHEMBL186988 | 0.68 | KDM4E (0.62) | KMT2AMEN1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164953-A | Asymmetric heptamethine quinoline cyanine fluorescent dye and application thereof | 河北大学 | 2024-06-11 | — | — | CN | disclosed |