SCHEMBL29230010

SCHEMBL29230010

CCCOc1ccccc1-c1nc(=O)c(N)c(N)[nH]1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 19/20 0.56
PDE4A P27815 2/20 0.56
PDE4B Q07343 2/20 0.56
PDE4C Q08493 2/20 0.56
PDE4D Q08499 2/20 0.56
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
PDE2A O00408 1/20 0.56
PDE6D O43924 1/20 0.56
USP2 O75604 1/20 0.56
PDE9A O76083 1/20 0.56
LMNA P02545 1/20 0.56
CYP1A2 P05177 1/20 0.56
MAPT P10636 1/20 0.56
HPGD P15428 1/20 0.56
ALOX15 P16050 1/20 0.56
PDE6A P16499 1/20 0.56
PDE6G P18545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7029661 0.82 PDE5A (0.62) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7931425 0.80 PDE5A (0.56) PDE5APDE4APDE4BPDE4CPDE4D
Sulfuric Acid SCHEMBL7718120 0.77 PDE5A (0.56) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7402899 0.77 PDE5A (0.56) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL4452818 0.77 PDE5A (0.68) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7959294 0.76 PDE5A (0.56) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7962891 0.76 PDE5A (0.57) PDE5APDE4APDE4BPDE4CPDE4D
Zaprinast SCHEMBL50329 0.76 PDE5A (0.56) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7076702 0.76 PDE5A (0.62) PDE5APDE4APDE4BPDE4CPDE4D
Zaprinast SCHEMBL30276335 0.76 PDE5A (0.56) PDE5APDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924627-A Thickened oil viscosity reducer and preparation method thereof 克拉玛依双信有限责任公司 2024-04-26 CN claimed
CN-117924627-B Thickened oil viscosity reducer and preparation method thereof 克拉玛依双信有限责任公司 2024-06-07 CN disclosed
CN-117924627-A Thickened oil viscosity reducer and preparation method thereof 克拉玛依双信有限责任公司 2024-04-26 CN disclosed