Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20711244 | 0.87 | KDM4E (0.37) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL28261017 | 0.81 | KMT2A (0.39) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL20711246 | 0.77 | KDM4E (0.35) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL20806026 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28948699 | 0.70 | FFAR1 (0.36) | FFAR1 | |
| Hydrochloric Acid SCHEMBL28027474 | 0.68 | ALOX5 (0.36) | ALDH1A1EP300FFAR1 | |
| SCHEMBL18680932 | 0.67 | SCD (0.54) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL16093587 | 0.67 | ALDH1A1 (0.67) | ALDH1A1LMNACYP1A2KMT2AHPGD | |
| SCHEMBL8976539 | 0.66 | KDM4E (0.39) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL6072289 | 0.65 | ALDH1A1 (0.45) | KDM4EKDM5CKDM4CKDM2AKDM3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |