Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 7/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.40 |
| ▸ | BIRC8 | Q96P09 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24665904 | 1.00 | CFD (0.47) | CFDTACR1CPA1CPA2CPA4 | |
| SCHEMBL30341369 | 0.88 | TACR1 (0.40) | CFDTACR1CPA1CPA2CPA4 | |
| SCHEMBL29230687 | 0.88 | TACR1 (0.40) | CFDTACR1CPA1CPA2CPA4 | |
| SCHEMBL24665979 | 0.88 | TACR1 (0.40) | CFDTACR1CPA1CPA2CPA4 | |
| SCHEMBL24666350 | 0.87 | CFD (0.42) | CFDTACR1KCNH2DPP8DPP7 | |
| SCHEMBL26833180 | 0.87 | CFD (0.42) | CFDTACR1KCNH2DPP8DPP7 | |
| SCHEMBL26837486 | 0.87 | CFD (0.46) | CFDTACR1CPA1CPA2CPA4 | |
| SCHEMBL26832850 | 0.86 | FAP (0.44) | CFDTACR1AADATDPP8DPP7 | |
| SCHEMBL24666347 | 0.84 | TACR1 (0.41) | CFDTACR1AADATDPP8DPP7 | |
| SCHEMBL24666349 | 0.83 | TACR1 (0.40) | CFDTACR1AADATDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |