Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.45 |
| ▸ | RET | P07949 | 6/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163998 | 1.00 | NR1H2 (0.45) | NR1H2NR1H3GPR119RETGBA1 | |
| SCHEMBL24986790 | 0.81 | GPR119 (0.49) | NR1H2NR1H3GPR119RETGBA1 | |
| SCHEMBL30164198 | 0.81 | GPR119 (0.49) | NR1H2NR1H3GPR119RETGBA1 | |
| SCHEMBL30163884 | 0.79 | GPR119 (0.45) | NR1H2NR1H3GPR119RETEGLN2 | |
| SCHEMBL24984504 | 0.79 | GPR119 (0.45) | NR1H2NR1H3GPR119RETEGLN2 | |
| SCHEMBL30163917 | 0.78 | GPR119 (0.46) | NR1H2NR1H3GPR119RETKCNH2 | |
| SCHEMBL29232158 | 0.78 | GPR119 (0.46) | NR1H2NR1H3GPR119RETKCNH2 | |
| SCHEMBL4573148 | 0.77 | GRIA1 (0.49) | NR1H2NR1H3GPR119RETCKS1B | |
| SCHEMBL3538823 | 0.77 | KDM4E (0.59) | NR1H2NR1H3GPR119ALDH1A1MAPT | |
| SCHEMBL24984528 | 0.76 | MEN1 (0.42) | NR1H2NR1H3GPR119RETCKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159530-A | Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling | 康福治疗有限公司 | 2024-06-07 | — | — | CN | disclosed |