Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320403 | 0.84 | LRRK2 (0.31) | CHRM1LRRK2MAT2A | |
| SCHEMBL23320405 | 0.82 | LRRK2 (0.37) | JAK2JAK1LRRK2 | |
| SCHEMBL30943209 | 0.76 | MDM4 (0.36) | JAK2JAK1MAT2A | |
| SCHEMBL23320355 | 0.76 | MDM4 (0.36) | JAK2JAK1MAT2A | |
| SCHEMBL28620742 | 0.71 | MAT2A (0.32) | CHRM1MAT2A | |
| SCHEMBL23320377 | 0.70 | NAMPT (0.45) | — | |
| SCHEMBL30943196 | 0.70 | NAMPT (0.45) | — | |
| SCHEMBL28637402 | 0.67 | ATR (0.39) | — | |
| SCHEMBL23320390 | 0.61 | CNR1 (0.41) | LRRK2 | |
| SCHEMBL22931772 | 0.60 | LIPE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |