Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320377 | 1.00 | NAMPT (0.45) | NAMPT | |
| SCHEMBL23320353 | 0.84 | NAMPT (0.60) | NAMPT | |
| SCHEMBL23320405 | 0.80 | LRRK2 (0.37) | — | |
| SCHEMBL23320455 | 0.76 | ROCK2 (0.50) | NAMPT | |
| SCHEMBL30943209 | 0.73 | MDM4 (0.36) | — | |
| SCHEMBL23320355 | 0.73 | MDM4 (0.36) | — | |
| SCHEMBL23320403 | 0.72 | LRRK2 (0.31) | — | |
| SCHEMBL23320440 | 0.72 | NAMPT (0.63) | NAMPT | |
| SCHEMBL23320390 | 0.70 | CNR1 (0.41) | — | |
| SCHEMBL29232474 | 0.70 | JAK2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |