Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29235853 | 0.74 | ALDH1A1 (0.32) | HRH3SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL29235625 | 0.73 | HRH3 (0.30) | HRH3 | |
| SCHEMBL29235539 | 0.72 | SMN1; SMN2 (0.39) | MAOAACHESMN1; SMN2MEN1KMT2A | |
| SCHEMBL30888336 | 0.72 | SMN1; SMN2 (0.38) | MAOAACHESMN1; SMN2 | |
| SCHEMBL29235918 | 0.70 | — | — | |
| SCHEMBL29708577 | 0.70 | USP30 (0.33) | HRH3 | |
| SCHEMBL30888305 | 0.70 | SMN1; SMN2 (0.36) | CRBNSMN1; SMN2 | |
| SCHEMBL13162766 | 0.69 | CSF1R (0.43) | HRH3MAOAACHESMN1; SMN2KMT2A | |
| SCHEMBL29708869 | 0.68 | USP30 (0.32) | MAOAACHE | |
| SCHEMBL29598733 | 0.67 | SMN1; SMN2 (0.38) | MAOAACHESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |